Author

J. Durrant

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Pharmacology & Toxicology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:protein structure· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1

Frequent Co-Authors

A. F. O'Donnell· 1 shared A. Van Wieren· 1 shared C. Shang· 1 shared D. G. Chandrashekarappa· 1 shared E. M. Jordahl· 1 shared H. Green· 1 shared J. Young· 1 shared K. G. Oppenheimer· 1 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCell Biology

A. F. O'Donnell

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Hexokinase 2 localizes to the nucleus in response to glucose limitation but does not regulate gene expression

M. A. Lesko, D. G. Chandrashekarappa, E. M. Jordahl, K. G. Oppenheimer, R. W. Bowman, C. Shang, J. Durrant, M. C. Schmidt, A. F. O'Donnell

This study uses live-cell imaging to show that Hxk2 localizes to the nucleus under glucose limitation, contradicting previous findings, and finds it does not regulate gene expression.

bioRxiv · Nov 30, 2022 · PreprintCell Biology

Computational and experimental analyses of alanine racemase suggest new avenues for developing allosteric small-molecule antibiotics

A. Van Wieren, J. Durrant, S. Majumdar

The paper identifies a new potential drug-binding site in alanine racemase by combining computational analysis and experimental validation, suggesting it for allosteric antibiotic development.

bioRxiv · Oct 29, 2022Biochemistry

FPocketWeb: Protein pocket hunting in a web browser

Y. Kochnev, J. Durrant

FPocketWeb provides a web-based tool for detecting protein pockets without requiring installation or data upload to third-party servers.

bioRxiv · May 27, 2022Pharmacology & Toxicology

BINANA 2.0: Characterizing Protein/Ligand Interactions in Python and JavaScript

J. Young, N. Garikipati, J. Durrant

BINANA 2.0 provides a web-based tool for analyzing protein/ligand interactions using Python and JavaScript, enabling visualization and analysis in web browsers.

bioRxiv · Sep 10, 2021Biochemistry

DeepFrag: An Open-Source Browser App for Deep-Learning Lead Optimization

H. Green, J. Durrant

DeepFrag provides a browser-based app for lead optimization using deep learning, eliminating the need for coding or server uploads.

Journal of Chemical Information and Modeling · May 24, 2021Peer-reviewedPharmacology & Toxicology