Author

J. E. Ferrell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 4 Approach:experimental assay· 4 Organism:Xenopus· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1

Frequent Co-Authors

W. Y. C. Huang· 3 shared J. Kamenz· 2 shared Y. Chen· 2 shared A. Moskaleva· 1 shared A. R. K. Reddy· 1 shared J.-H. Huang· 1 shared L. Gelens· 1 shared M. Kang· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersBiophysics

W. Y. C. Huang

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Author profile →

5 papers

Recent·Most cited

Robust trigger wave speed in Xenopus cytoplasmic extracts

J.-H. Huang, Y. Chen, W. Y. C. Huang, S. Tabatabaee, J. E. Ferrell

The paper investigates trigger wave speed robustness in Xenopus extracts, finding it invariant despite cytoplasmic concentration changes and proposing a model explaining this behavior.

bioRxiv · Dec 22, 2023 · PreprintBiophysics

Membrane localization accelerates association under conditions relevant to cellular signaling

W. Y. C. Huang, S. G. Boxer, J. E. Ferrell

The paper compares association rates of a signaling reaction in solution and on membranes, finding membrane localization significantly increases rates in larger cells.

bioRxiv · Oct 22, 2022Biophysics

Cytoplasmic organization promotes protein diffusion

W. Y. C. Huang, X. Cheng, J. E. Ferrell

The paper studies how cytoplasmic organization affects protein diffusion using Xenopus laevis egg extracts, finding that organization increases diffusion speed for protein-sized molecules.

bioRxiv · Jul 9, 2021Biophysics

Bistable, biphasic regulation of PP2A-B55 accounts for the dynamics of mitotic substrate phosphorylation

J. Kamenz, L. Gelens, J. E. Ferrell

The paper shows PP2A-B55 acts as a bistable switch and is regulated biphasically by Cdk1, influencing mitotic substrate phosphorylation dynamics.

Current Biology · Feb 1, 2021Peer-reviewedCell Biology

The apparent requirement for protein synthesis during G2 phase is due to checkpoint activation

S. Lockhead, A. Moskaleva, J. Kamenz, Y. Chen, M. Kang, A. R. K. Reddy, S. Santos, J. E. Ferrell

The study shows cycloheximide arrests cells in G2 phase due to p38 MAPK activation, not protein synthesis inhibition, indicating G2 protein synthesis is not required for mitotic entry.

bioRxiv · Dec 3, 2019Cell Biology