Lipid nanoparticles delivering constitutively active STING mRNA as a novel anti-cancer therapeutic approach
W. Liu, M.-G. Alameh, J. F. Yang, J. R. Xu, P. J. Lin, Y. K. Tam, D. Weissman, J. You
This study uses mRNA lipid nanoparticles to deliver an active STING mutant to treat STING-deficient cancers, enhancing immune response and inducing cancer cell death.
bioRxiv · Jan 8, 2022 · PreprintBioengineering