Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
12 papers
Recent·Most cited
Z. Ou, L. Li, P. Ren, T. Zhou, F. He, J. Chen, H. Cai, X. Han, Y. Wu, J. Li, X. Li, Q. Tan, W. Li, Q. Chen, N. Zhang, , H. Yan
This study uses spatiotemporal transcriptomics to analyze immune dynamics in E. multilocularis infected mouse liver, identifying key immune cell roles and shifts in immune strategy during infection.
Advanced Science · Feb 22, 2025Peer-reviewedImmunology
R. Wang, T. E. Senay, T. T. Luo, J. M. Regan, N. Salisbury, D. Galloway, J. You
This study identifies MCPyV protein ALTO as a factor that modulates the STING-TBK1 pathway to limit viral replication and maintain persistent infection.
bioRxiv · Apr 5, 2024Microbiology
W. Mi, J. You, L. Li, L. Zhu, X. Xia, L. Yang, F. Li, Y. Xu, J. Bi, P. Liu, L. Chen, F. Li
This study shows BET inhibition in liver cancer reduces proliferation by inducing GDH1-dependent glutamine metabolic changes, suggesting a therapeutic strategy combining BET and OXPHOS inhibitors.
bioRxiv · Mar 20, 2024Cancer Biology
L. Wu, J. Chen, Y. Wu, W. Hao, J. You
This study identifies hepatic androgen receptor as a mediator of glucagon sensitivity in female mice, revealing its role in glucose and lipid metabolism via the PGC1α/ERRα/mitochondria axis.
bioRxiv · Nov 2, 2023Physiology
J. K. Allen, M. A. Gonzalez, J. Kaur, M. Smith, J. You, G. Yang, D. Zha, Z. Tian, A. Al-Shami, C. Shi, J. J. Molldrem, T. Heffernan
This study develops fully human bispecific antibodies that effectively block Omicron variant pseudovirus infections, showing improved neutralization compared to monoclonal antibodies.
bioRxiv · Mar 7, 2023 · PreprintBiochemistry
J. You, W. Xiao, Y. Zhou, L. Ye, G. Yu, P. Yu, X. Zhang, Z. He, Y. Xiang, X. Sang, Y.-F. Li, F. Zhao, Y. Ling, G. He, T. Zhang
This study identifies the APC/CTAD1-WL1-NAL1 pathway as a regulator of leaf width in rice and shows that mutations in WL1 lead to leaf width variation.
bioRxiv · Jan 10, 2022 · PreprintPlant Biology
W. Liu, M.-G. Alameh, J. F. Yang, J. R. Xu, P. J. Lin, Y. K. Tam, D. Weissman, J. You
This study uses mRNA lipid nanoparticles to deliver an active STING mutant to treat STING-deficient cancers, enhancing immune response and inducing cancer cell death.
bioRxiv · Jan 8, 2022 · PreprintBioengineering
M. M. Drozdz, A. S. Doane, R. Alkallas, G. Desman, R. Bareja, M. Reilly, J. Bang, M. Yusupova, J. You, J. Z. Wang, A. Verma, K. Aguirre, E. Kane, I. R. Watson, O. Elemento, , J. H. Zippin
The paper identifies a nuclear cAMP microdomain that suppresses tumor growth by inhibiting YAP in the Hippo pathway.
bioRxiv · Nov 15, 2021Cancer Biology
J. You, H. Frazer, S. Sayyar, Z. Chen, X. Liu, A. Taylor, B. Filippi, I. Wise, C. Hodge, G. Wallace, G. Sutton
This paper develops an in-situ printing system using a human platelet lysate-based bio-adhesive to treat corneal perforations, showing improved adhesion, burst pressure, and faster healing in rabbits compared to cyanoacrylate glue.
bioRxiv · Sep 13, 2021Bioengineering
R. K. Singh, Y. Pei, Z. L. Lamplugh, K. Sun, Y. Yuan, P. Lieberman, J. You, E. S. Robertson
This study shows that KSHV-encoded vCyclin modulates HIF1α levels in hypoxia to promote DNA replication and cell proliferation.
bioRxiv · Aug 12, 2020Microbiology
R. Zhang, Y. He, L. Yao, J. Chen, S. Zhu, X. Rao, P. Tang, J. You, L. Zhang, G. Hua, F. Ju, L. Wu
This study shows that metformin chlorination byproducts are toxic to nematodes, human cells, and mice, and identifies boiling and activated carbon as effective removal methods.
bioRxiv · Jul 18, 2020 · PreprintPharmacology & Toxicology
Q. Huang, S. Hao, X. Yao, J. You, X. Li, D. Lai, C. Han, J. Schilling, K. Y. Hwa, S. Thyparambil, J. Whitin, H. J. Cohen, H. J. Chubb, S. R. Ceresnak, D. B. McElhinney, , X. B. Ling
This paper develops and validates an LC/MS/MS method to quantify ceramides and dihydroceramides in human serum, revealing unique gestational patterns during pregnancy.
bioRxiv · Feb 24, 2020 · PreprintBiochemistry