The cell cycle regulatory DREAM complex is disrupted by high expression of oncogenic B-Myb
A. N. Iness, J. Felthousen, V. Ananthapadmanabhan, K. Z. Guiley, M. Dozmorov, S. M. Rubin, L. Litovchick
This study shows that B-Myb disrupts the DREAM complex by affecting LIN52 protein levels and DYRK1A kinase activity, contributing to cancer progression.
Oncogene · Sep 11, 2018Peer-reviewedCancer Biology