Author

A. N. Iness

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

J. Felthousen· 1 shared K. Z. Guiley· 1 shared L. Litovchick· 1 shared M. Dozmorov· 1 shared S. M. Rubin· 1 shared V. Ananthapadmanabhan· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

J. Felthousen

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1 paper

Recent·Most cited

Cancer BiologyOncogenePeer-reviewedSep 11, 2018

The cell cycle regulatory DREAM complex is disrupted by high expression of oncogenic B-Myb

A. N. Iness, J. Felthousen, V. Ananthapadmanabhan…·L. Litovchick

This study shows that B-Myb disrupts the DREAM complex by affecting LIN52 protein levels and DYRK1A kinase activity, contributing to cancer progression.

DOI 10.1038/s41388-018-0490-y

humanbulk RNA-seq

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