NOD1 mediates non-canonical inflammasome processing of interleukin-18 in epithelial cells to Helicobacter pylori infection.
L. S. Tran, L. Ying, K. D'Costa, G. Wray-McCann, G. Kerr, L. Le, C. C. Allison, J. Ferrand, H. Chaudhry, J. Emery, A. De Paoli, S. Creed, M. Kaparakis-Liaskos, J. Como, J. Dowling, , R. L. Ferrero
This study identifies NOD1 as a key regulator of IL-18 processing in epithelial cells during Helicobacter pylori infection, independent of canonical inflammasome proteins.
bioRxiv · Mar 24, 2019 · PreprintImmunology