Metabolic and Epigenomic Regulation of Th17/Treg Balance by the Polyamine Pathway
C. Wang, A. Wagner, J. Fessler, J. Avila-Pacheco, J. Karminski, P. Thakore, S. Zaghouani, K. Pierce, L. Bod, A. Schnell, D. DeTomaso, N. Ron-Harel, M. Haigis, D. Puleston, E. Pearce, , V. Kuchroo
The paper identifies the polyamine pathway as a regulator of Th17/Treg balance, showing its impact on inflammation and T cell phenotype.
bioRxiv · Jan 23, 2020 · PreprintImmunology