Spatiotemporal heterogeneity of glioblastoma is dictated by microenvironmental interference
V. M. Ravi, P. Will, J. Kuekelhaus, N. Sun, K. Joseph, H. Salie, J. von Ehr, L. Vollmer, J. K. Benotmane, N. Neidert, M. Follo, F. Scherer, J. Goeldner, S. P. Behringer, P. Franco, , D. H. Heiland
This study identifies microenvironmental factors driving transcriptional heterogeneity in glioblastomas through spatial transcriptomics, metabolomics, and proteomics.
bioRxiv · Feb 16, 2021 · PreprintCancer Biology