Author

J. Holbrook

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Wong· 1 shared D. Peckham· 1 shared F. Martinon· 1 shared H. H. Jarosz-Griffiths· 1 shared M. F. McDermott· 1 shared S. Lara-Reyna· 1 shared S. Pathak· 1 shared S. Savic· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperImmunology

C. Wong

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1 paper

Recent·Most cited

Excessive ENaC-mediated sodium influx drives NLRP3 inflammasome-dependent autoinflammation in Cystic Fibrosis

T. Scambler, H. H. Jarosz-Griffiths, S. Lara-Reyna, S. Pathak, C. Wong, J. Holbrook, F. Martinon, S. Savic, D. Peckham, M. F. McDermott

This study shows that excessive ENaC-mediated sodium influx drives NLRP3 inflammasome-dependent autoinflammation in Cystic Fibrosis, with potential therapeutic implications for lung inflammation.

bioRxiv · Nov 6, 2018 · PreprintImmunology