Human UFSP1 is an active protease that regulates UFM1 maturation and UFMylation
D. Millrine, T. Cummings, S. P. Matthews, J. J. Peter, H. Magnussen, T. Macartney, F. Lamoliatte, A. Knebel, Y. Kulathu
The paper identifies UFSP1 as an active protease that matures UFM1 and regulates UFMylation, distinguishing it from UFSP2 in substrate specificity and function.
bioRxiv · Feb 28, 2022Biochemistry