Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
10 papers
Recent·Most cited
A. S. Chawla, H. J. Watt, S. A. Schattgen, N. Skariah, I. Saha, K. Warrick, M. Ogawa, F. Lamoliatte, J. Strid, A. Copland, S. Pryde, E. Knatko, K. D. Rasmussen, K. Kikuchi, P. G. Thomas, , M. Swamy
The paper identifies a conserved mechanism, RePrESS, by which autoreactive innate-like T cells maintain tolerance through rewiring of the TCR signalosome.
bioRxiv · Sep 1, 2023 · PreprintImmunology
R. S. Jadav, F. Weiland, S. M. Noordermeer, T. Carroll, Y. Gao, J. Wang, H. Zhou, F. Lamoliatte, I. Munoz, R. Toth, T. Macartney, F. Brown, C. J. Hastie, C. Alabert, H. van Attikum, , J. Rouse
The paper identifies novel ATR-dependent phospho-proteomic targets and reveals new biomarkers and genome maintenance factors through screening with ATR inhibitors.
bioRxiv · Apr 3, 2023Biochemistry
S. A. Abdul Rehman, E. Di Nisio, C. Cazzaniga, O. Antico, A. Knebel, C. Johnson, F. Lamoliatte, R. Negri, M. Muqit, V. De Cesare
The paper identifies and characterizes non-canonical E2 conjugating enzymes that ubiquitylate serine and threonine instead of lysine, revealing their target substrate and catalytic mechanism.
bioRxiv · Mar 5, 2023 · PreprintBiochemistry
S. M. Lange, M. R. McFarland, F. Lamoliatte, D. Kwasna, L. Shen, I. Wallace, I. Cole, L. A. Armstrong, A. Knebel, C. Johnson, V. De Cesare, Y. Kulathu
This paper develops a pipeline to study branched ubiquitin chains, identifies debranching enzymes, and reveals their roles in VCP/p97 processes and DNA damage responses.
bioRxiv · Jan 10, 2023Biochemistry
J. Rouse, M. Gregorczyk, G. Pastore, P. Lis, S. Lange, F. Lamoliatte, T. Macartney, R. Toth, F. Brown, J. Hastie, D. Durocher
This study identifies C21ORF2 as a regulatory subunit of NEK1, showing that their interaction is critical for NEK1 function and that mutations disrupt this interaction, linking it to disease.
bioRxiv · Aug 31, 2022 · PreprintBiochemistry
T. Snelling, N. Shpiro, R. Gourlay, F. Lamoliatte, P. Cohen
This study identifies how ADP-heptose activates ALPK1 and downstream inflammatory pathways through coordinated action of TRAF6, TRAF2/c-IAP1, and LUBAC.
bioRxiv · Jul 19, 2022Immunology
D. Millrine, T. Cummings, S. P. Matthews, J. J. Peter, H. Magnussen, T. Macartney, F. Lamoliatte, A. Knebel, Y. Kulathu
The paper identifies UFSP1 as an active protease that matures UFM1 and regulates UFMylation, distinguishing it from UFSP2 in substrate specificity and function.
bioRxiv · Feb 28, 2022Biochemistry
J. J. Peter, H. M. Magnussen, P. A. DaRosa, D. Millrine, S. P. Matthews, F. Lamoliatte, R. Sundaramoorthy, R. R. Kopito, Y. Kulathu
The paper identifies the minimal requirements for protein UFMylation and reveals the regulatory mechanism of an atypical scaffold-type E3 ligase complex.
bioRxiv · Jan 31, 2022 · PreprintBiochemistry
E. Rusilowicz-Jones, J. Jardine, A. Kallinos, A. Pinto-Fernandez, F. Guenther, M. Giurrandino, F. G. Barone, K. McCarron, C. J. Burke, A. Murad, A. Martinez, E. Marcassa, M. Gersch, A. Buckmelter, K. Kayser-Bricker, , M. J. Clague
The paper identifies a USP30 inhibitor that mimics genetic loss of USP30, revealing its role in regulating mitochondrial ubiquitylation and mitophagy through TOM complex components.
Life Science Alliance · Jul 7, 2020Peer-reviewedCell Biology
T. Heunis, F. Lamoliatte, J.-L. Marin Rubio, A. Dannoura, M. Trost
The paper quantifies ubiquitin chain types in murine tissues using optimized Ub-AQUA-PRM, revealing tissue-specific differences and enrichment of atypical K33 chains in contractile tissues.
bioRxiv · Mar 18, 2020Biochemistry