Author

J. Jaskiewicz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Assay:proteomics· 2 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:rat· 1

Frequent Co-Authors

C. B. Shoemaker· 2 shared J. M. Tremblay· 2 shared S. Tzipori· 2 shared A. Manjula-Basavanna· 1 shared A. Sheoran· 1 shared A. Shrestha· 1 shared A. Swei· 1 shared C. Giem· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBioengineering

C. B. Shoemaker

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Enteric pharmacokinetics of monomeric and multimeric camelid nanobody single-domain antibodies

M. Debatis, H. Danz, J. M. Tremblay, K. Gaspie, R. Kudej, V. Vigdorovich, N. Sather, J. Jaskiewicz, S. Tzipori, C. B. Shoemaker

This study compares the functional and structural stability of monomeric and multimeric camelid VHHs in vitro and in vivo, showing some VHHs can match the stability of conventional antibodies in the gut.

bioRxiv · May 15, 2023Bioengineering

Single domain antibodies against enteric pathogen virulence factors are active as curli fiber fusions on probiotic E. coli Nissle 1917

I. Gelfat, Y. Aqeel, J. M. Tremblay, J. Jaskiewicz, A. Shrestha, J. N. Lee, S. Hu, X. Qian, L. Magoun, A. Sheoran, D. Bedenice, C. Giem, A. Manjula-Basavanna, M. S. Osbourne, S. Tzipori, , N. S. Joshi

The paper develops VHH-based therapeutics displayed on probiotic E. coli Nissle 1917 to target enteric pathogens, showing they can bind and neutralize virulence factors.

bioRxiv · Jun 18, 2021Microbiology

Cryopreservation of Infectious Cryptosporidium parvum Oocysts

J. Jaskiewicz, R. Sandlin, A. Swei, G. Widmer, M. Toner, T. Saul

This study develops a method to cryopreserve Cryptosporidium parvum oocysts using ultra-fast cooling, maintaining their viability and infectivity for several weeks.

bioRxiv · May 31, 2018Microbiology