Author

J. Kierfeld

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:imaging· 1

Frequent Co-Authors

F. Schwietert· 3 shared A. Musacchio· 1 shared F. S. Kratz· 1 shared L. K. Heydenreich· 1 shared L. Moellerherm· 1 shared M. Dogterom· 1 shared P. J. Huis in 't Veld· 1 shared V. A. Volkov· 1 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

8 top collaborators · 12 mutual co-author links

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3 shared papersBiophysics

F. Schwietert

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4 papers

Recent·Most cited

Enhancing Robustness, Precision and Speed of Traction Force Microscopy with Machine Learning

F. S. Kratz, L. Moellerherm, J. Kierfeld

This paper introduces a deep convolutional neural network to improve the robustness, precision, and speed of traction force microscopy by solving an inverse elastic problem more efficiently than traditional methods.

bioRxiv · Sep 2, 2022Biophysics

Dynamics and length distributions of microtubules with a multistep catastrophe mechanism

F. Schwietert, L. K. Heydenreich, J. Kierfeld

This study extends the Dogterom-Leibler model to analyze how a multistep catastrophe mechanism affects microtubule length distributions in bounded and unbounded growth regimes.

bioRxiv · Aug 19, 2022Biophysics

Strain stiffening of Ndc80 complexes attached to microtubule plus ends

F. Schwietert, V. A. Volkov, P. J. Huis in 't Veld, M. Dogterom, A. Musacchio, J. Kierfeld

The paper measures strain stiffening of Ndc80 complexes under tension from depolymerizing microtubules, showing it is robust to mutations and linked to structural features and thermal fluctuations.

bioRxiv · Mar 15, 2022Biophysics

Bistability and oscillations in cooperative microtubule and kinetochore dynamics in the mitotic spindle

F. Schwietert, J. Kierfeld

This paper models mitotic spindle dynamics to show bistability and oscillations arise from microtubule-kinetochore interactions and linker stiffness.

bioRxiv · Mar 12, 2019Biophysics