RNA polymerase redistribution and increased gene dosage support growth in E. coli strains with a minimal number of ribosomal RNA operons
J. Fan, H. El Sayyed, O. J. Pambos, M. Stracy, J. Kyropoulos, A. N. Kapanidis
The paper investigates RNAP redistribution and increased gene dosage in E. coli with reduced rrn operons, showing RNAP clusters form near remaining rrn operons and growth defects are minimized.
bioRxiv · Feb 10, 2022 · PreprintMicrobiology