Insulin-like growth factor-2 does not improve behavioral deficits in mouse and rat models of Angelman Syndrome
E. Berg, S. Petkova, H. A. Born, A. Adhikari, A. E. Anderson, J. L. Silverman
This study tests IGF-2's ability to improve behavioral deficits in AS mouse and rat models but finds limited and non-enduring effects.
bioRxiv · Aug 13, 2021Pharmacology & Toxicology