Mechanosensitive calcium signaling promotes epithelial tight junction remodeling by activating RhoA
S. Varadarajan, R. E. Stephenson, E. R. Misterovich, J. L. Wu, I. S. Erofeev, A. B. Goryachev, A. L. Miller
The paper shows that mechanosensitive calcium flashes trigger RhoA activation, leading to tight junction remodeling in response to mechanical stress in Xenopus laevis epithelial cells.
bioRxiv · May 18, 2021Cell Biology