Genetically variant human pluripotent stem cells selectively eliminate wild-type counterparts through YAP-mediated cell competition
C. J. Price, D. Stavish, P. J. Gokhale, S. Sargeant, J. Lacey, T. A. Rodriguez, I. Barbaric
This study shows genetically variant human pluripotent stem cells outcompete wild-type cells via YAP-mediated mechanisms leading to their elimination.
bioRxiv · Nov 25, 2019Cell Biology