Author

J. Linton

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Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Rongvaux· 1 shared D. Kuppers· 1 shared K. McKenna· 1 shared P. PADDISON· 1 shared S. Ortiz· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperBioengineering

A. Rongvaux

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1 paper

Recent·Most cited

Gene knock-outs in human CD34+ hematopoietic stem and progenitor cells and in the human immune system of mice

D. Kuppers, J. Linton, S. Ortiz, K. McKenna, A. Rongvaux, P. PADDISON

The paper develops a method to efficiently edit human CD34+ HSPCs before transplantation, enabling gene knock-outs in the human immune system of mice with high efficiency and without affecting engraftment potential.

bioRxiv · Oct 6, 2022Bioengineering