RNA- and ATAC-sequencing Reveals a Unique CD83+ Microglial Population Focally Depleted in Parkinson's Disease
Zena K. Chatila, A. Yadav, J. Mares, Xena E. Flowers, Taekyung Yun, M. Rashid, Ryan Talcoff, Z. Pelly, Ya Zhang, Philip L. De Jager, Andrew F. Teich, Rui M. Costa, Estela Área-Gómez, G. Martins, Roy N. Alcalay, , Serge Przedborski
The paper uses single-nucleus RNA- and ATAC-sequencing to identify a CD83+ microglial subpopulation depleted in Parkinson's disease, with implications for neuronal vulnerability.
bioRxiv · May 17, 2023 · PreprintNeuroscience