Author

W. Sippl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. G. Kansy· 1 shared A. Piee-Staffa· 1 shared A.-H. M. Mustafa· 1 shared C. Brachetti· 1 shared C. Vorreiter· 1 shared D. Misiak· 1 shared E. Ghazy· 1 shared F. Wiley· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperPharmacology & Toxicology

A. G. Kansy

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

More than just an Eagle Killer: The freshwater cyanobacterium Aetokthonos hydrillicola produces highly toxic dolastatin derivatives

M. Schwark, J. A. Martinez Yerena, K. Roehrborn, P. Hrouzek, P. Divoka, L. Stenclova, K. Delawska, H. Enke, C. Vorreiter, F. Wiley, W. Sippl, R. Sobotka, S. Saha, S. B. Wilde, J. Mares, T. H. J. Niedermeyer

This paper identifies and characterizes new toxic dolastatin derivatives produced by the freshwater cyanobacterium Aetokthonos hydrillicola, revealing its potential threat to ecosystems and human health.

bioRxiv · Apr 12, 2023Microbiology

IGF2BP1 induces high-risk neuroblastoma and forms a druggable feedforward loop with MYCN promoting 17q oncogene expression

S. Hagemann, D. Misiak, J. L. Bell, T. Fuchs, M. I. Lederer, N. Bley, M. Haemmerle, E. Ghazy, W. Sippl, J. H. Schulte, S. Huettelmaier

This paper identifies a druggable feedforward loop between IGF2BP1 and MYCN in high-risk neuroblastoma that promotes oncogene expression and relapse, suggesting combined targeting as a therapeutic strategy.

bioRxiv · Mar 18, 2023Cancer Biology

Novel hydroxamic acid derivative induces apoptosis and constrains autophagy in leukemic cells

M. A. Fischer, A.-H. M. Mustafa, K. Hausmann, R. Ashry, A. G. Kansy, M. C. Liebl, C. Brachetti, A. Piee-Staffa, M. Zessin, H. S. Ibrahim, T. G. Hofmann, M. Schutkowski, W. Sippl, O. H. Kramer

This paper synthesizes novel HDAC inhibitors that show nanomolar activity against class I HDACs and induce apoptosis while constraining autophagy in leukemic cells.

bioRxiv · Mar 9, 2023Pharmacology & Toxicology