Conserved lipid and small molecule modulation of COQ8 reveals regulation of the ancient UbiB family
A. Reidenbach, Z. Kemmerer, D. Aydin, A. Jochem, M. McDevitt, P. Hutchins, E. Wilkerson, J. Stark, J. Stefely, I. Johnson, C. Bingman, J. Markley, J. Coon, M. Dal Peraro, D. Pagliarini
This study identifies lipid and small molecule modulators of COQ8, an ancient UbiB family protein, and establishes a chemical genetic system to study its role in CoQ biosynthesis.
bioRxiv · Jun 13, 2017Biochemistry