Author

D. Aydin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. B. Seven· 1 shared A. Inoue· 1 shared A. Jochem· 1 shared A. Reidenbach· 1 shared B. K. Kobilka· 1 shared B. L. Roth· 1 shared C. Bingman· 1 shared D. Pagliarini· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiophysics

A. B. Seven

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Author profile →

2 papers

Recent·Most cited

Structural insights into distinct signaling profiles of the μOR activated by diverse agonists

Q. Qu, W. Huang, D. Aydin, J. M. Paggi, A. B. Seven, H. Wang, S. Chakraborty, T. Che, J. F. DiBerto, M. J. Robertson, A. Inoue, B. L. Roth, S. Majumdar, R. O. Dror, B. K. Kobilka, G. Skiniotis

This study compares the structural and signaling differences between two μOR agonists, lofentanil and mitragynine pseudoindoxyl, revealing how their distinct binding modes lead to different G protein and β-arrestin activation profiles.

bioRxiv · Dec 7, 2021 · PreprintBiophysics

Conserved lipid and small molecule modulation of COQ8 reveals regulation of the ancient UbiB family

A. Reidenbach, Z. Kemmerer, D. Aydin, A. Jochem, M. McDevitt, P. Hutchins, E. Wilkerson, J. Stark, J. Stefely, I. Johnson, C. Bingman, J. Markley, J. Coon, M. Dal Peraro, D. Pagliarini

This study identifies lipid and small molecule modulators of COQ8, an ancient UbiB family protein, and establishes a chemical genetic system to study its role in CoQ biosynthesis.

bioRxiv · Jun 13, 2017Biochemistry