Kinesin-5 promotes microtubule nucleation and assembly by stabilizing a lattice-competent conformation of tubulin
G.-Y. Chen, A. B. Asenjo, Y. Chen, J. Mascaro, D. F. J. Arginteanu, H. J. Sosa, W. O. Hancock
This study identifies Eg5 as a microtubule polymerase that promotes microtubule growth by inducing a curved-to-straight transition in tubulin.
bioRxiv · Jan 14, 2019Biophysics