Author

J. McBroome

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 4 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:deep learning· 2 Organism:Drosophila· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Organism:virus· 2 Assay:whole-genome sequencing· 2 Research Focus:clustering· 1

Frequent Co-Authors

R. Corbett-Detig· 4 shared A. S. Hinrichs· 3 shared Y. Turakhia· 3 shared C. Ruis· 2 shared C. Ye· 2 shared A. de Bernardi Schneider· 1 shared A. della Torre· 1 shared A. N. O'Toole· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersEvolutionary Biology

R. Corbett-Detig

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Author profile →

5 papers

Recent·Most cited

Automated Agnostic Designation of Pathogen Lineages

J. McBroome, A. de Bernardi Schneider, C. Roemer, M. T. Wolfinger, A. S. Hinrichs, A. N. O'Toole, C. Ruis, Y. Turakhia, A. Rambaut, R. Corbett-Detig

The paper introduces an automated method for pathogen lineage designation using phylogenetic trees, offering a consistent alternative to manual curation.

bioRxiv · Feb 3, 2023 · PreprintEvolutionary Biology

Mutational spectra distinguish SARS-CoV-2 replication niches

C. Ruis, T. P. Peacock, L. M. Polo, D. Masone, M. Soledad Alvarez, A. S. Hinrichs, Y. Turakhia, C. Ye, J. McBroome, R. Corbett-Detig, J. Parkhill, R. A. Floto

The paper analyzes SARS-CoV-2 mutational spectra to infer replication niches, finding reduced G>T mutations in Omicron linked to upper respiratory tract replication.

bioRxiv · Sep 27, 2022 · PreprintMicrobiology

Pandemic-Scale Phylogenomics Reveals Elevated Recombination Rates in the SARS-CoV-2 Spike Region

Y. Turakhia, B. Thornlow, A. S. Hinrichs, J. Mcbroome, N. Ayala, C. Ye, N. De Maio, D. Haussler, R. Lanfear, R. Corbett-Detig

The paper develops a novel phylogenomic method to detect recombination events in SARS-CoV-2 genomes, identifying 606 recombination events across 1.6M samples with 2.7% of genomes showing recombinant ancestry, primarily in the Spike protein region.

bioRxiv · Aug 4, 2021 · PreprintEvolutionary Biology

Fine-scale position effects shape the distribution of inversion breakpoints in Drosophila melanogaster

J. McBroome, D. Liang, R. Corbett-Detig

The paper examines the fine-scale distribution of inversion breakpoints in Drosophila melanogaster and identifies factors influencing their fitness impacts.

bioRxiv · Oct 7, 2019Evolutionary Biology

Fine-mapping complex inversion breakpoints and investigating somatic pairing in the Anopheles gambiae species complex using proximity-ligation sequencing

R. B. Corbett-Detig, I. Said, M. Calzetta, M. Genetti, J. Mcbroome, N. W. Maurer, V. Petrarca, A. della Torre, N. J. Besansky

The paper fine-maps inversion breakpoints in Anopheles gambiae species complex using Hi-C sequencing and investigates somatic pairing disruption near these breakpoints.

bioRxiv · Jun 7, 2019Evolutionary Biology