HCMV glycoprotein B nucleoside-modified mRNA vaccine elicits antibody responses with greater durability and breadth than MF59-adjuvanted gB protein immunization
C. Nelson, J. Jenks, N. Pardi, M. Goodwin, H. Roark, W. Edwards, J. McClellan, J. Pollara, D. Weissman, S. Permar
This study compares gB mRNA-LNP vaccine with gB protein vaccines, finding that mRNA-LNP elicits more durable and broadly reactive antibodies against HCMV glycoprotein B.
bioRxiv · Oct 8, 2019Immunology