Author

W. Edwards

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

D. Weissman· 2 shared N. Pardi· 2 shared A. Brown· 1 shared A. Eaton· 1 shared A. Newman· 1 shared A. P. Piedade· 1 shared A. P. Rochford· 1 shared A. Schäfer· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

D. Weissman

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A disease-associated gene desert orchestrates macrophage inflammatory responses via ETS2

C. T. Stankey, C. Bourges, T. Turner-Stokes, A. P. Piedade, C. Palmer-Jones, I. Papa, M. Silva dos Santos, L. O. Randzavola, L. Speidel, E. C. Parkes, W. Edwards, A. P. Rochford, C. Murray, J. I. MacRae, P. Skoglund, , J. C. Lee

The paper identifies ETS2 as a master regulator of macrophage inflammatory responses linked to a disease-associated gene desert and shows how modulating this pathway could improve treatment of inflammatory diseases.

Nature · Jun 5, 2024Peer-reviewedImmunology

Perilipin 5 interacts with Fatp4 at membrane contact sites to promote lipid droplet-to-mitochondria fatty acid transport

G. E. Miner, C. M. So, W. Edwards, L. E. Herring, R. A. Coleman, E. L. Klett, S. Cohen

This study identifies Plin5 and Fatp4 interaction at LD-mitochondria contacts, showing phosphorylation of Plin5 and Fatp4's role in fatty acid transport during starvation.

bioRxiv · Feb 3, 2022Cell Biology

Breadth of SARS-CoV-2 Neutralization and Protection Induced by a Nanoparticle Vaccine

D. Li, D. R. Martinez, A. Schäfer, H. Chen, M. Barr, L. L. Sutherland, E. Lee, R. Parks, D. Mielke, W. Edwards, A. Newman, K. W. Bock, M. Minai, B. M. Nagata, M. Gagne, , B. F. Haynes

This study shows a nanoparticle vaccine induces broad neutralizing antibodies against multiple SARS-CoV-2 variants and protects non-human primates and mice from viral challenges.

bioRxiv · Jan 26, 2022Immunology

HCMV glycoprotein B nucleoside-modified mRNA vaccine elicits antibody responses with greater durability and breadth than MF59-adjuvanted gB protein immunization

C. Nelson, J. Jenks, N. Pardi, M. Goodwin, H. Roark, W. Edwards, J. McClellan, J. Pollara, D. Weissman, S. Permar

This study compares gB mRNA-LNP vaccine with gB protein vaccines, finding that mRNA-LNP elicits more durable and broadly reactive antibodies against HCMV glycoprotein B.

bioRxiv · Oct 8, 2019Immunology