ATP dependent DNA transport within cohesin: Scc2 clamps DNA on top of engaged heads while Scc3 promotes entrapment within the SMC-kleisin ring
J. E. Collier, B.-G. Lee, M. Brunet-Roig, S. Yatskevich, N. J. Petela, J. Metson, M. Voulgaris, A. Gonzalez Llamazares, J. Lowe, K. A. Nasmyth
The paper demonstrates that Scc2 clamps DNA in cohesin's E-S/E-K compartments while Scc3 facilitates DNA entrapment within the SMC-kleisin ring during DNA loop extrusion.
bioRxiv · Jun 3, 2020 · PreprintBiochemistry