p62-mediated Selective Autophagy Endows Virus-transformed Cells with Insusceptibility to DNA Damage under Oxidative Stress
L. Wang, M. Howell, A. Sparks-Wallace, C. Hawkins, C. Nicksic, C. Kohne, K. Hall, J. Moorman, Z. Q. Yao, S. Ning
This study shows that p62-mediated selective autophagy in virus-transformed cells protects against DNA damage under oxidative stress by regulating CHK1 and RAD51 protein stability.
bioRxiv · Feb 27, 2019Cancer Biology