C. Hawkins

The paper identifies aberrant DNA repair as a vulnerability in H3.3-mutant brain tumors, showing that PNKP-mediated repair is specific to mutant cells and offers therapeutic potential.

This study identifies ID1 upregulation in DIPG tumor cells and shows that CBD can reduce ID1-driven invasiveness in vitro and in vivo.

This study shows that p62-mediated selective autophagy in virus-transformed cells protects against DNA damage under oxidative stress by regulating CHK1 and RAD51 protein stability.