Blocks in tricarboxylic acid cycle of Salmonella enterica cause global perturbation of carbon storage, motility and host-pathogen-interaction
J. Noster, N. Hansmeier, M. Persicke, T.-C. Chao, R. Kurre, J. Popp, V. Liss, T. Reuter, M. Hensel
This study shows that fumarase deficiency in Salmonella enterica disrupts carbon metabolism, leading to glycogen accumulation, altered motility, and increased macrophage phagocytosis.
bioRxiv · Nov 6, 2019Microbiology