Author

J. Patten

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

C. J. Donahue· 2 shared H. Mori· 2 shared R. A. Davey· 2 shared R. Boytz· 2 shared A.-L. Barabasi· 1 shared C. O'Leary· 1 shared D. Anderson· 1 shared D. J. Lacount· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMicrobiology

C. J. Donahue

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Author profile →

2 papers

Recent·Most cited

CAPG is required for Ebola virus infection by controlling virus egress from infected cells.

H. Mori, J. M. Connell, C. J. Donahue, R. Boytz, J. Patten, D. W. Leung, D. J. Lacount, R. A. Davey

This study identifies CAPG as a host factor required for Ebola virus infection by stabilizing actin filaments and facilitating viral egress from infected cells.

bioRxiv · Apr 10, 2022Microbiology

Identification of druggable host targets needed for SARS-CoV-2 infection by combined pharmacological evaluation and cellular network directed prioritization both in vitro and in vivo.

J. Patten, P. T. Keiser, D. M. Gysi, G. Menichetti, H. Mori, C. J. Donahue, X. Gan, I. F. do Valle, K. Geoghegan-Barek, M. Anantpadma, R. Boytz, J. L. Berrigan, S. Hulsey-Stubbs, K. T. Ayazika, C. O'Leary, , R. A. Davey

The paper identifies 389 small molecules and 813 host targets that inhibit SARS-CoV-2 infection through in vitro and in vivo testing, using computational integration of drug activity and cellular networks.

bioRxiv · Apr 20, 2021 · PreprintMicrobiology