Author

J. Pimentel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

C. C. Faria· 2 shared C. Custodia· 2 shared E. Paisana· 2 shared J. Miguens· 2 shared J. T. Barata· 2 shared R. Cascao· 2 shared R. Roque· 2 shared T. Carvalho· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

C. C. Faria

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

UBE2C promotes leptomeningeal dissemination and is a therapeutic target in brain metastatic disease

E. Paisana, R. Cascao, C. Custodia, N. Qin, D. Picard, D. Pauck, T. Carvalho, P. Ruivo, C. Barreto, D. Doutel, J. Cabecadas, R. Roque, J. Pimentel, J. Miguens, J. T. Barata, C. C. Faria

This study identifies UBE2C as a driver of leptomeningeal dissemination in brain metastases and shows that PI3K/mTOR inhibition can prevent its metastatic effects.

bioRxiv · Oct 4, 2022 · PreprintCancer Biology

Patient-derived models of brain metastases recapitulate the histopathology and biology of human metastatic cancers

C. C. Faria, C. Custodia, R. Cascao, E. Paisana, T. Carvalho, P. Pereira, R. Roque, J. Pimentel, J. Miguens, J. T. Barata

This study develops patient-derived xenograft models of brain metastases that replicate human cancer biology and respond to targeted therapies.

bioRxiv · Nov 26, 2020 · PreprintCancer Biology

Smaug membraneless organelles regulate mitochondrial function

A. J. Fernandez-Alvarez, M. G. Thomas, M. L. Pascual, M. Habif, J. Pimentel, A. A. Corbat, J. P. Pessoa, P. E. La Spina, L. Boscaglia, A. Plessis, M. Carmo-Fonseca, H. E. Grecco, M. Casado, G. L. Boccaccio

This study shows Smaug1 membraneless organelles regulate mitochondrial function by controlling mRNA localization and mitochondrial respiration.

bioRxiv · Jul 31, 2020 · PreprintCell Biology