Lysosomal swelling and lysis mediate delivery of C3 toxins to their cytoplasmic targets
S. Grinstein, M. Turner, J. Plumb, R. Merrill, J. Westman
This study investigates how C3 toxins enter host cells by tracking fluorescently labeled C3larvinA and shows that lysosomal swelling and lysis are critical for toxin delivery to the cytoplasm.
bioRxiv · Oct 11, 2022Microbiology