Author

J. Roques

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

J. L. IOVANNA· 3 shared N. J. Dusetti· 3 shared O. Gayet· 3 shared M. Bigonnet· 2 shared R. Nicolle· 2 shared A. Dereynies· 1 shared A. El kaoutari· 1 shared A. Elkaoutari· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersCancer Biology

J. L. IOVANNA

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3 papers

Recent·Most cited

Metabolomic profiling of pancreatic adenocarcinoma reveals fundamental clinical features

J. L. IOVANNA, A. El kaoutari, N. Fraunhoffer, O. Hoare, C. Teyssedou, O. Gayet, J. Roques, G. A. Lomberk, R. A. Urrutia, N. J. Dusetti

This study identifies a metabolic signature in pancreatic adenocarcinoma that predicts clinical outcomes and drug resistance, suggesting metabolic targeting as a therapeutic strategy.

bioRxiv · Feb 1, 2021Cancer Biology

Establishment of a pancreatic adenocarcinoma molecular gradient (PAMG) that predicts the clinical outcome of pancreatic cancer

R. Nicolle, Y. Blum, P. Duconseil, C. Vanbrugghe, N. Brandone, F. Poizat, J. Roques, M. Bigonnet, O. Gayet, M. Rubis, N. Elarouci, L. Armenoult, M. Ayadi, A. Dereynies, M. Giovannini, , N. J. Dusetti

This paper develops a transcriptomic gradient (PAMG) to predict pancreatic cancer aggressiveness and treatment response using patient-derived xenografts and clinical data.

bioRxiv · Mar 25, 2020Cancer Biology

Basal-like and Classical cells coexistence in pancreatic cancer revealed by single cell analysis

N. J. Dusetti, N. Juiz, A. Elkaoutari, M. Bigonnet, O. Gayet, J. Roques, R. Nicolle, J. L. Iovanna

The paper uses single-cell transcriptomic analysis to show that basal-like and classical cells coexist in pancreatic cancer tumors, revealing unexpected heterogeneity.

bioRxiv · Jan 7, 2020Cancer Biology