BH3 Profiling Identifies Selective BCL-2 Dependence of Adult Early T-cell Progenitor (ETP) Subtype of Acute Lymphoblastic Leukemia (ALL) Patients
E. A. Olesinski, K. S. Bhatia, J. S. Garica, N. Jain, A. Letai, M. Konopleva, S. Bhatt
This study identifies BCL-2 dependence in adult ETP-ALL and co-dependence on BCL-2 and BCL-XL in adult non-ETP-ALL, suggesting targeted therapies.
bioRxiv · Aug 19, 2021 · PreprintCancer Biology