S. Bhatt

Bayesian inference of phylogenetic distances: revisiting the eigenvalue approach

The paper develops a Bayesian method to infer phylogenetic distances incorporating heterotachy and rate variation, finding evidence for a two-domain theory of eukaryotic origins.

DFNA5-mediated pyroptosis is a driver for venetoclax and azacytidine synergy in myeloid leukemia

This study shows that DFNA5-mediated pyroptosis contributes to the synergy between venetoclax and azacytidine in myeloid leukemia, beyond apoptosis.

Mycobacterium tuberculosis infection elevates SLIT2 expression to modulate oxidative stress responses in macrophages

This study shows that Mycobacterium tuberculosis infection increases SLIT2 expression in macrophages through p38/JNK pathway activation and reduced H3K27me3 repression, leading to elevated ROS levels via Vanin1.

The cost of sympatry: spatio-temporal patterns in leopard dietary and physiological responses to tiger competition in Rajaji Tiger Reserve, India

The paper examines how tiger competition affects leopard diet and physiology in Rajaji Tiger Reserve, finding that sympatry with tigers increases nutritional stress in leopards.

BH3 Profiling Identifies Selective BCL-2 Dependence of Adult Early T-cell Progenitor (ETP) Subtype of Acute Lymphoblastic Leukemia (ALL) Patients

This study identifies BCL-2 dependence in adult ETP-ALL and co-dependence on BCL-2 and BCL-XL in adult non-ETP-ALL, suggesting targeted therapies.

AzuCR RNA modulates carbon metabolism as a dual-function RNA in Escherichia coli

The paper identifies AzuCR RNA in E. coli as a dual-function RNA that regulates carbon metabolism by both encoding a protein and modulating gene expression through base pairing.

Effects of faecal inorganic contents in accurate measures of stress and nutrition hormone in large felines: implications for physiological assessments in free-ranging animals

This study examines how inorganic matter in feces affects stress and nutrition hormone measurements in tigers and lions, proposing corrections to improve accuracy.

Assessing tiger corridor functionality with landscape genetics and modelling across Terai-Arc Landscape, India

The paper assesses tiger corridor functionality in the Terai-Arc Landscape using landscape genetics and GIS modelling, identifying critical corridors and subpopulations for conservation.

MAPPING TRENDS IN INSECTICIDE RESISTANCE PHENOTYPES IN AFRICAN MALARIA VECTORS

The paper maps trends in insecticide resistance in African malaria vectors using Bayesian geostatistical models and 6423 resistance observations across Africa.

Co-localization and confinement of ecto-nucleotidases modulate extracellular adenosine nucleotide pools

This study uses reaction-diffusion simulations to show that confinement and charge effects in narrow extracellular spaces influence the kinetics of coupled nucleotidase reactions.

Targeted DNA transposition using a dCas9-transposase fusion protein

This study demonstrates efficient targeted DNA transposition using a dCas9-transposase fusion protein, achieving precise integration near gRNA binding sites.

Iron nanoparticle-labeled murine mesenchymal stromal cells in an osteoarthritic model persists and demonstrates anti-inflammatory mechanism of action

This study tracks iron nanoparticle-labeled MSCs in an OA model, showing they persist in joints and increase homeostatic macrophages, reducing inflammation.

A practive faeces collection protocol for multidisciplinary research in wildlife science

The paper describes a feces collection protocol for wildlife research, achieving high success rates in DNA amplification and offering a universal framework for multidisciplinary use.

Antimicrobial Efficacy and Safety of a Novel Gas Plasma-Activated Catheter Lock Solution

This study evaluates a novel antibiotic-free gas plasma-activated catheter lock solution, showing it effectively eradicates biofilm microbes and is less toxic to human cells than a standard solution.