RNase HI depletion strongly potentiates cell killing by rifampicin in mycobacteria
A. Al-Zubaidi, C.-Y. Cheung, G. M. Cook, G. Taiaroa, V. Mizrahi, J. S. Lott, S. S. Dawes
This paper shows that reducing RNase HI activity in mycobacteria increases sensitivity to rifampicin, suggesting RNase HI as a target for new antibiotics.
bioRxiv · Jul 14, 2021Microbiology