BK polyomavirus (BKPyV) is a risk factor for bladder cancer through induction of APOBEC3-mediated genomic damage
S. C. Baker, A. S. Mason, R. G. Slip, K. T. Skinner, A. Macdonald, O. Masood, R. S. Harris, T. R. Fenton, M. Periyasamy, S. Ali, J. Southgate
This study shows BKPyV infection increases APOBEC3-mediated genomic damage in urothelial cells, contributing to bladder cancer risk in immunocompromised individuals.
bioRxiv · May 13, 2021Cancer Biology