Prevention and reversion of pancreatic tumorigenesis through a differentiation-based mechanism
N. M. Krah, D. Yugawa, J. Straley, C. V. E. Wright, R. J. MacDonald, L. C. Murtaugh
This study shows that maintaining Ptf1a activity can prevent and reverse Kras-driven pancreatic tumorigenesis in mice, suggesting differentiation-based strategies for cancer treatment.
bioRxiv · Nov 19, 2017Cancer Biology