Cancer BiologybioRxiv
Prevention and reversion of pancreatic tumorigenesis through a differentiation-based mechanism
N. M. Krah, D. Yugawa, J. Straley…·L. C. Murtaugh
This study shows that maintaining Ptf1a activity can prevent and reverse Kras-driven pancreatic tumorigenesis in mice, suggesting differentiation-based strategies for cancer treatment.
DOI 10.1016/j.devcel.2019.07.012