Author

J. T. DeWitt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Organism:yeast· 3 Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

D. R. Kellogg· 3 shared A. Brambila· 1 shared B. E. Prichard· 1 shared J. C. Chinwuba· 1 shared R. A. Sommer· 1 shared R. Tan· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 7 mutual co-author links

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3 shared papersCell Biology

D. R. Kellogg

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3 papers

Recent·Most cited

Hyperactive Ras disrupts cell size control and a key step in cell cycle entry in budding yeast

J. T. DeWitt, J. C. Chinwuba, D. R. Kellogg

This study identifies how hyperactive Ras in budding yeast disrupts cell size control by impairing the transcription of late G1 phase cyclins, revealing PKA-independent mechanisms.

bioRxiv · Mar 6, 2023Cell Biology

New roles for an old cyclin in control of cell cycle entry and cell size

A. Brambila, B. E. Prichard, J. T. DeWitt, D. R. Kellogg

This study reveals that Cln3 influences late G1 phase cyclin accumulation post-transcriptionally and has mitotic functions affecting cell size, challenging existing models of cell cycle control.

bioRxiv · Aug 12, 2022 · PreprintCell Biology

Growth-dependent signals drive an increase in early G1 cyclin concentration to link cell cycle entry with cell growth

R. A. Sommer, J. T. DeWitt, R. Tan, D. R. Kellogg

The paper investigates the role of Cln3 and Whi5 in linking cell cycle entry to growth in budding yeast, finding that Cln3 concentration increases with growth to drive cell cycle entry.

eLife · Oct 29, 2021Peer-reviewedCell Biology