Author

J. Tom

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Lyczek· 1 shared A. M. Rangwala· 1 shared B.-T. Berger· 1 shared H. Philipose· 1 shared J. D. Chodera· 1 shared J. Guo· 1 shared M. A. Seeliger· 1 shared M. B. Robers· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. Lyczek

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1 paper

Recent·Most cited

Mutation in Abl kinase with altered drug binding kinetics indicates a novel mechanism of imatinib resistance

A. Lyczek, B.-T. Berger, A. M. Rangwala, Y. Paung, J. Tom, H. Philipose, J. Guo, S. K. Albanese, M. B. Robers, S. Knapp, J. D. Chodera, M. A. Seeliger

The paper identifies a mutation in Abl kinase that causes imatinib resistance through altered drug dissociation kinetics rather than reduced binding affinity.

bioRxiv · Jun 28, 2021Biochemistry