ADP heptose, a novel pathogen-associated molecular pattern associated with Helicobacter pylori type 4 secretion
L. Pfannkuch, R. Hurwitz, J. Traulsen, P. Kosma, M. Schmid, T. F. Meyer
The paper identifies ADP heptose as the key PAMP in Helicobacter pylori that activates NF-κB via the Alpk1-TIFA axis, showing 100-fold stronger activity than previously proposed HBP.
bioRxiv · Aug 31, 2018Microbiology