Cellular Immune Responses Induced by Subretinal AAV Gene Transfer can be Restrained by the Subretinal Associated Immune Inhibition Mechanism
J. VENDOMELE, G. A. CHAUVEAU, D. DALKARA, A. Galy, S. FISSON
This study shows that subretinal AAV8 injection induces proinflammatory T-cell responses against transgene products, which can be modulated by the subretinal associated immune inhibition mechanism.
bioRxiv · Dec 30, 2022 · PreprintImmunology