Author

J. Wienke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

B. B. van Rijn· 2 shared F. van Wijk· 2 shared L. Brouwers· 2 shared M. Mokry· 2 shared P. G. Nikkels· 2 shared A. Franx· 1 shared A. J. R. Heck· 1 shared A. M. Cornel· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

B. B. van Rijn

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Author profile →

3 papers

Recent·Most cited

Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy

J. Wienke, L. L. Visser, W. M. Kholosy, K. M. Keller, M. Barisa, S. Munnings-Tomes, E. Carlton, E. Poon, A. Rodriguez, R. Bernardi, F. Van den Ham, S. R. Van Hooff, Y. A. H. Matser, M. Tas, K. P. S. Langenberg, , J. J Molenaar

The paper uses single-cell RNA sequencing to analyze neuroblastoma and identifies the NECTIN2-TIGIT axis as a potential target for immunotherapy.

bioRxiv · Jul 15, 2022Cancer Biology

Human placental bed transcriptomic profiling reveals inflammatory activation of endothelial cells in preeclampsia

L. Brouwers, J. Wienke, M. Mokry, P. G. Nikkels, T. E. Vogelvang, A. Franx, F. van Wijk, B. B. van Rijn

The paper identifies inflammatory activation of endothelial cells in preeclampsia through transcriptomic profiling and systemic biomarker analysis.

bioRxiv · Oct 18, 2021 · PreprintImmunology

Human regulatory T cells at the maternal-fetal interface show functional site-specific adaptation with tumor-infiltrating-like features

J. Wienke, L. Brouwers, L. M. van der Burg, M. Mokry, R. C. Scholman, P. G. Nikkels, B. B. van Rijn, F. van Wijk

This study identifies a distinct transcriptional profile of uterine regulatory T cells at the maternal-fetal interface, showing features similar to tumor-infiltrating Tregs.

bioRxiv · Nov 5, 2019Immunology