Dishevelled 2 coordinates aortic Notch signaling through primitive myeloid and hemogenic endothelial cells during hematopoietic stem cell specification
Kelsey A. Carpenter, Amber D. Ide, Jacquelyn Jacobs, Emma J. Rudisel, Nina Sheely, Margarita Parada-Kusz, Stephanie J. Grainger
This study identifies Dishevelled 2 as a regulator of HSC specification in zebrafish by coordinating Notch signaling and immune cell support during the endothelial-to-hematopoietic transition.
bioRxiv · Sep 30, 2026 · PreprintDevelopmental Biology