Author
Broad Institute
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Mutual co-authors in cluster
5 papers
Recent·Most cited
Kelsey A. Carpenter, Amber D. Ide, Jacquelyn Jacobs…·Stephanie J. Grainger
This study identifies Dishevelled 2 as a regulator of HSC specification in zebrafish by coordinating Notch signaling and immune cell support during the endothelial-to-hematopoietic transition.
Margarita Parada-Kusz, Samuel J. Wattrus, Jacquelyn Jacobs…·Deborah Tan Hung
This study identifies kainate receptors' role in coordinating primitive hematopoiesis and hemogenic niche organization in zebrafish, showing their impact on hematopoietic stem cell development through endothelial Notch signaling.
Emily R. Goering, Anne E. Clatworthy, Margarita Parada-Kusz…·Deborah Tan Hung
The paper shows that Kmo produces 3-HK, which promotes macrophage lysosomal acidification via kainate receptor antagonism, enhancing resistance to Salmonella infection.
Margarita Parada-Kusz, Anne E. Clatworthy, Emily R. Goering…·Deborah Tan Hung
The paper identifies 3-hydroxy-kynurenine as a tryptophan metabolite that enhances host survival during bacterial infection by modulating kainate receptors in macrophages.
Margarita Parada-Kusz, Anne E. Clatworthy, Elliott J. Hagedorn…·Miguel L. Allende
This study xenografts murine bone marrow cells into zebrafish embryos to study hematopoiesis and host-pathogen interactions, showing successful integration and immune response.