Overexpression of miR-424(322)/-503 induces severe dilated cardiomyopathy by regulating the fatty acid oxidation gene expression program
Shreesti Shrestha, Jiayi Chen, Xiaopeng Shen, Rui Liang, Jahnvi Rajput, Marcello Tosso, Hoang Vu, Anirban Roy, Chin‐Yo Lin, Ryan L. Boudreau, Ashok Kumar, Bradley K. McConnell, Yu Liu
This study shows that overexpression of miR-424(322)/-503 in the heart causes severe dilated cardiomyopathy by disrupting fatty acid oxidation and metabolic function.
bioRxiv · Aug 18, 2026 · PreprintMolecular Biology