Author

Jake Thomas

University of Bonn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Ago Szabo· 1 shared Alessia De’Felice· 1 shared Amber Moodley· 1 shared Andreas SchlitzeriD· 1 shared Ángela Sanzo-MachucaiD· 1 shared Anna Csala· 1 shared Arnaud BourreilleiD· 1 shared Aurélie JoussaumeiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

Ago Szabo

Mutual co-authors in cluster

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2 papers

Recent·Most cited

A JAK-STAT-activated myeloid hub at ulceration sites underlies resistance to anti-TNF therapy in Crohn's disease

Thomas Laurent, Monika Mykhaylyshyn, Jake Thomas, Gaëlle Bériou, Lucas Otero-Laudouar, Lucas Brusselle, Aurélie Joussaume, Cécile Braudeau, Justine Chevreuil, Cynthia Fourgeux, Laurence Bouchet‐Delbos, Martin Braud, Nicolas Chapelle, Mathieu Uzzan, Pablo Canales-Herrerías, , J. P. D. Martin

The paper identifies a JAK-STAT-activated myeloid subset, IFIM, associated with anti-TNF resistance in Crohn's disease and proposes JAK inhibition as a therapeutic strategy.

bioRxiv · Feb 13, 2026 · PreprintImmunology

Low Replication Capacity Virus Is Preferentially Transmitted In Mother-To-Child-Transmission But Not In Adult-To-Adult-Transmission Of HIV-1

Emily Adland, Louisa Iselin, Francesca Roxburgh, Jane Millar, Anna Csala, Vanessa Naidoo, Christie Noble, Jake Thomas, Alessia De’Felice, Ago Szabo, Nick Grayson, Amber Moodley, Krista Dong, Bruce Walker, Thumbi Ndung’u, , Philip Goulder

The paper compares viral replicative capacity in mother-to-child and adult-to-adult HIV-1 transmission, finding lower replicative capacity in MTCT viruses.

bioRxiv · Jan 3, 2019 · PreprintImmunology